-<ClinicalUseIssue xmlns="http://hl7.org/fhir">
 <!-- ISO name: (id is generated on the fly)  -->
 <id value="SPIOInhaler28mg-d3e49"/>
 <type value="interaction"/>
-<subject>
 </subject>
 <!-- ISO name: /MedicinalProduct/Interactions/InteractionsText  -->
 <description value="Based on the interaction profile for tobramycin following intravenous and aerosolised administration, concurrent and/or sequential use of SPIO Inhaler is not recommended with other medicinal products with nephrotoxic or ototoxic potential."/>
 <!-- ISO name: /MedicinalProduct/Interactions  -->
-<interaction>
 <!-- ISO name: /MedicinalProduct/Interactions/Interactant  -->
-<interactant>
 <!-- ISO name: /MedicinalProduct/Interactions/Interactant  -->
-<itemCodeableConcept>
-<coding>
 <system value="http://ema.europa.eu/fhir/interactant"/>
 <code value="medicinalproductswithnephrotoxicpotential"/>
 </coding>
 </itemCodeableConcept>
 </interactant>
 <!-- ISO name: /MedicinalProduct/Interactions/Interactant  -->
-<interactant>
 <!-- ISO name: /MedicinalProduct/Interactions/Interactant  -->
-<itemCodeableConcept>
-<coding>
 <system value="http://ema.europa.eu/fhir/interactant"/>
 <code value="medicinalproductswithototoxicpotential"/>
 </coding>
 </itemCodeableConcept>
 </interactant>
 <!-- ISO name: /MedicinalProduct/Interactions/InteractionsType  -->
-<type>
-<coding>
 <system value="http://ema.europa.eu/fhir/interactionsType"/>
 <code value="drug-druginteraction"/>
 </coding>
 </type>
 <!-- ISO name: /MedicinalProduct/Interactions/ManagementActions  -->
-<management>
-<coding>
 <system value="http://ema.europa.eu/fhir/managementactions"/>
 <code value="Concurrentusenotrecommended"/>
 </coding>
 </management>
 </interaction>
 </ClinicalUseIssue>